1-[2-(S)-amino-3-biphenyl-4-yl-propionyl]-pyrrolidine-2-(S)-carbonitrile

This compound is a synthetic small molecule known as 1-[2-(S)-amino‑3‑biphenyl‑4‑yl‑propionyl]‑pyrrolidine‑2‑(S)‑carbonitrile. It is structurally related to dipeptidomimetic inhibitors and has been identified in chemical biology datasets as a potent inhibitor of the enzyme dipeptidyl peptidase 4 (DPP-IV, also known as DPP4). DPP-IV inhibitors are an established class of drugs for the treatment of type 2 diabetes mellitus, where they act by prolonging the activity of incretin hormones, thereby enhancing insulin secretion and lowering blood glucose. This compound appears in research databases but does not have evidence of clinical development or approval as a marketed pharmaceutical[1][3][8].

Other names

(2S)-1[(2S)− amino− 3(4-biphenylyl)propanoyl]pyrrolidine− carbonitrile